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Assay Detail

CHEMBL3876388

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Displacement of [3H]a,b-MeATP from rat urinary bladder P2X receptor measured after 120 mins by scintillation counting method
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Rattus norvegicus
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Structure-anticonvulsant activity studies in the group of (E)-N-cinnamoyl aminoalkanols derivatives monosubstituted in phenyl ring with 4-Cl, 4-CH3 or 2-CH3.
Gunia-Krzyżak A, Żelaszczyk D, Rapacz A, Żesławska E, Waszkielewicz AM, Pańczyk K, Słoczyńska K, Pękala E, Nitek W, Filipek B, Marona H.
Bioorg Med Chem (2017) 25 : 471 -482
PubMed 27876250 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 8.72 8.72

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL132722 DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER 1 8.72

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL132722 DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER IC50 = 1.9 nM 8.72