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Assay Detail

CHEMBL3877192

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of FAK (unknown origin)
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Non-kinase targets of protein kinase inhibitors.
Munoz L.
Nat Rev Drug Discov (2017) 16 : 424 -440
PubMed 28280261 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 8.24 8.70

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL472212 1 8.70
CHEMBL1995703 1 7.77

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL472212 IC50 = 2.0 nM 8.70
CHEMBL1995703 IC50 = 17.0 nM 7.77