Assay Detail
Binding
CHEMBL3878219
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Inhibition of Plasmodium falciparum DHODH
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Plasmodium falciparum |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Dihydroorotate dehydrogenase: A drug target for the development of antimalarials.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 7.70 | 7.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL217893 | — | — | 1 | 7.70 |
| CHEMBL2234191 | — | — | 1 | 7.70 |
| CHEMBL2234182 | — | — | 1 | 7.70 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL217893 | — | IC50 | = | 20.0 | nM | 7.70 |
| CHEMBL2234191 | — | IC50 | = | 20.0 | nM | 7.70 |
| CHEMBL2234182 | — | IC50 | = | 20.0 | nM | 7.70 |