Assay Detail
Binding
CHEMBL3880174
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of rat NaV1.3
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Sodium channel protein type 3 subunit alpha (CHEMBL4966) ↗| Type | SINGLE PROTEIN |
| Organism | Rattus norvegicus |
Publication
Bicyclic derivatives as modulators of voltage gated ion channels
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 7.82 | 7.82 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL507974 | TETRODOTOXIN | 3.0 | 1 | 7.82 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL507974 | TETRODOTOXIN | IC50 | = | 15.0 | nM | 7.82 |