Assay Detail
Functional
CHEMBL3880950
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Antiparasitic activity against chloroquine-resistant/verapamil-sensitive Plasmodium falciparum Dd2
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Plasmodium falciparum |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Isoform Selective HDAC Inhibitors
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 8.02 | 9.22 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL468935 | — | — | 1 | 9.22 |
| CHEMBL511212 | — | — | 1 | 8.22 |
| CHEMBL387924 | — | — | 1 | 7.92 |
| CHEMBL227120 | — | — | 1 | 6.73 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL468935 | — | IC50 | = | 0.6 | nM | 9.22 |
| CHEMBL511212 | — | IC50 | = | 6.0 | nM | 8.22 |
| CHEMBL387924 | — | IC50 | = | 12.0 | nM | 7.92 |
| CHEMBL227120 | — | IC50 | = | 185.0 | nM | 6.73 |