Assay Detail
Binding
CHEMBL3882294
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of GTP/glutamate-induced bovine brain tubulin polymerization by coulter counting method
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Bos taurus |
| Confidence | 5 — Multiple protein complex / RNA |
| Curated By | Autocuration |
Publication
Synthesis and biological evaluation of analogs of the antimitotic marine natural product curacin A
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.53 | 6.77 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL56812 | — | — | 1 | 6.77 |
| CHEMBL89138 | CURACIN A | — | 1 | 6.28 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL56812 | — | IC50 | = | 170.0 | nM | 6.77 |
| CHEMBL89138 | CURACIN A | IC50 | = | 520.0 | nM | 6.28 |