Assay Detail
Binding
CHEMBL3888059
Review assay metadata, readout intent, target linkage, and publication context from the same page.
In vitro Erk5 : In vitro Erk5 binding assay: Ambit Kd values in nanomolar. Kd values generated by Ambit binding assay over a concentration range of the compound.
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Pyrimido-diazepinone kinase scaffold compounds and methods of treating disorders
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 7 | 6.90 | 7.72 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1673039 | — | — | 1 | 7.72 |
| CHEMBL3984135 | — | — | 1 | 7.30 |
| CHEMBL1673040 | — | — | 1 | 7.24 |
| CHEMBL1673046 | — | — | 1 | 7.10 |
| CHEMBL3986079 | — | — | 1 | 6.50 |
| CHEMBL3902758 | — | — | 1 | 6.26 |
| CHEMBL1672987 | — | — | 1 | 6.17 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1673039 | — | Kd | = | 19.0 | nM | 7.72 |
| CHEMBL3984135 | — | Kd | = | 50.0 | nM | 7.30 |
| CHEMBL1673040 | — | Kd | = | 57.0 | nM | 7.24 |
| CHEMBL1673046 | — | Kd | = | 80.0 | nM | 7.10 |
| CHEMBL3986079 | — | Kd | = | 320.0 | nM | 6.50 |
| CHEMBL3902758 | — | Kd | = | 550.0 | nM | 6.26 |
| CHEMBL1672987 | — | Kd | = | 670.0 | nM | 6.17 |