Assay Detail
Binding
CHEMBL3889050
Review assay metadata, readout intent, target linkage, and publication context from the same page.
In Vitro Inhibition Assay: In Vitro Inhibition of Tyrosine Kinases using a 10-point Titration Curve.
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Target
Proto-oncogene tyrosine-protein kinase receptor Ret (CHEMBL2041) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Ocular formulations for drug-delivery to the posterior segment of the eye
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 7.96 | 7.96 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL253969 | OSI-632 | 2.0 | 1 | 7.96 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL253969 | OSI-632 | IC50 | = | 11.1 | nM | 7.96 |