Assay Detail
Functional
CHEMBL3992015
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Potentiation of carboplatin induced DNA damage in human A549 cells expressing Rad51 assessed as carboplatin IC50 at 0.71 uM (Rvb IC50 = 20.14 uM)
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | A549 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Pharmaceutical formulations comprising salts of a protein kinase inhibitor and methods of using same
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 5.20 | 5.20 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2105685 | AMUVATINIB HYDROCHLORIDE | -1.0 | 1 | 5.20 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2105685 | AMUVATINIB HYDROCHLORIDE | IC50 | = | 6300.0 | nM | 5.20 |