Assay Detail
Functional
CHEMBL3993667
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Cytotoxicity against human MCF7 cells incubated for 72 hrs under hypoxic condition by MTT assay
11
Total Activities
11
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | MCF7 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Total Syntheses and Biological Activities of Vinylamycin Analogues.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 11 | 5.60 | 7.10 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3774991 | — | — | 1 | 7.10 |
| CHEMBL3775684 | — | — | 1 | 6.92 |
| CHEMBL4089929 | — | — | 1 | 5.57 |
| CHEMBL4071537 | — | — | 1 | 5.53 |
| CHEMBL4082065 | — | — | 1 | 5.33 |
| CHEMBL4101716 | — | — | 1 | 5.17 |
| CHEMBL4098570 | — | — | 1 | 5.15 |
| CHEMBL4097663 | — | — | 1 | 5.10 |
| CHEMBL888 | GEMCITABINE | 4.0 | 1 | 5.05 |
| CHEMBL4093985 | — | — | 1 | 5.04 |
| CHEMBL4083718 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3774991 | — | IC50 | = | 80.0 | nM | 7.10 |
| CHEMBL3775684 | — | IC50 | = | 120.0 | nM | 6.92 |
| CHEMBL4089929 | — | IC50 | = | 2690.0 | nM | 5.57 |
| CHEMBL4071537 | — | IC50 | = | 2930.0 | nM | 5.53 |
| CHEMBL4082065 | — | IC50 | = | 4690.0 | nM | 5.33 |
| CHEMBL4101716 | — | IC50 | = | 6810.0 | nM | 5.17 |
| CHEMBL4098570 | — | IC50 | = | 7020.0 | nM | 5.15 |
| CHEMBL4097663 | — | IC50 | = | 7980.0 | nM | 5.10 |
| CHEMBL888 | GEMCITABINE | IC50 | = | 8900.0 | nM | 5.05 |
| CHEMBL4093985 | — | IC50 | = | 9170.0 | nM | 5.04 |
| CHEMBL4083718 | — | IC50 | > | 20000.0 | nM | - |