Assay Detail
ADMET
CHEMBL3998850
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human ALK6 using casein as substrate in presence of 10 uM ATP by radiometric kinase assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Bone morphogenetic protein receptor type-1B (CHEMBL5476) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Identification of the First Selective Activin Receptor-Like Kinase 1 Inhibitor, a Reversible Version of L-783277.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 7.59 | 9.03 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL513147 | — | — | 1 | 9.03 |
| CHEMBL4099337 | — | — | 1 | 6.14 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL513147 | — | IC50 | = | 0.94 | nM | 9.03 |
| CHEMBL4099337 | — | IC50 | = | 727.0 | nM | 6.14 |