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Assay Detail

CHEMBL4001500

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Cytotoxic activity against human MCF7 cells assessed as reduction in cell viability
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type MCF7
Confidence 1 — Organism
Curated By Autocuration

Target

MCF7 (CHEMBL387)
Type CELL-LINE
Organism Homo sapiens

Publication

Identification of a diverse synthetic abietane diterpenoid library for anticancer activity.
Xu H, Liu L, Fan X, Zhang G, Li Y, Jiang B.
Bioorg Med Chem Lett (2017) 27 : 505 -510
PubMed 28011223 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.96 5.96

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4097148 1 5.96

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4097148 IC50 = 1100.0 nM 5.96