Assay Detail

CHEMBL4001502

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ADMET

Cytotoxic activity against human HL7702 cells

ChEMBL ↗

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Target

L02 (CHEMBL4296457) ↗

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Primary target L02

CHEMBL4296457

Anchored from Assay target.

Protein identity L02

Disease frame Disease evidence pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	ADMET
Organism	Homo sapiens
Cell Type	L02
Confidence	1 — Organism
Curated By	Autocuration

Target

L02 (CHEMBL4296457) ↗

Type	CELL-LINE
Organism	Homo sapiens

Publication

Identification of a diverse synthetic abietane diterpenoid library for anticancer activity.

Xu H, Liu L, Fan X, Zhang G, Li Y, Jiang B.
Bioorg Med Chem Lett (2017) 27 : 505 -510
PubMed 28011223 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
IC50	1	4.79	4.79

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL4097148	—	—	1	4.79

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL4097148	—	IC50	=	16100.0	nM	4.79