Assay Detail
Functional
CHEMBL4004404
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Cytotoxicity against human HepG2 cells assessed as growth inhibition after 48 hrs by MTT assay
10
Total Activities
10
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HepG2 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Alkaloids from the mangrove endophytic fungus Diaporthe phaseolorum SKS019.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 10 | 6.50 | 6.50 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL417 | EPIRUBICIN | 4.0 | 1 | 6.50 |
| CHEMBL4065704 | — | — | 1 | - |
| CHEMBL3898586 | — | — | 1 | - |
| CHEMBL4099125 | — | — | 1 | - |
| CHEMBL4088979 | — | — | 1 | - |
| CHEMBL4060761 | — | — | 1 | - |
| CHEMBL4096674 | — | — | 1 | - |
| CHEMBL4069446 | — | — | 1 | - |
| CHEMBL4104397 | — | — | 1 | - |
| CHEMBL4080161 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL417 | EPIRUBICIN | IC50 | = | 320.0 | nM | 6.50 |
| CHEMBL4065704 | — | IC50 | > | 50000.0 | nM | - |
| CHEMBL3898586 | — | IC50 | > | 50000.0 | nM | - |
| CHEMBL4099125 | — | IC50 | > | 50000.0 | nM | - |
| CHEMBL4088979 | — | IC50 | > | 50000.0 | nM | - |
| CHEMBL4060761 | — | IC50 | > | 50000.0 | nM | - |
| CHEMBL4096674 | — | IC50 | > | 50000.0 | nM | - |
| CHEMBL4069446 | — | IC50 | > | 50000.0 | nM | - |
| CHEMBL4104397 | — | IC50 | > | 50000.0 | nM | - |
| CHEMBL4080161 | — | IC50 | > | 50000.0 | nM | - |