Assay Detail
Functional
CHEMBL4006880
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Cytotoxicity against human HepG2 cells assessed as growth inhibition after 72 hrs by SRB assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HepG2 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Synthesis and biological evaluation of novel pyrazolic chalcone derivatives as novel hepatocellular carcinoma therapeutics.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 5.60 | 5.85 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4097239 | — | — | 1 | 5.85 |
| CHEMBL4074494 | — | — | 1 | 5.77 |
| CHEMBL4059933 | — | — | 1 | 5.47 |
| CHEMBL4101494 | — | — | 1 | 5.32 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4097239 | — | IC50 | = | 1400.0 | nM | 5.85 |
| CHEMBL4074494 | — | IC50 | = | 1700.0 | nM | 5.77 |
| CHEMBL4059933 | — | IC50 | = | 3400.0 | nM | 5.47 |
| CHEMBL4101494 | — | IC50 | = | 4800.0 | nM | 5.32 |