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Assay Detail

CHEMBL4006927

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Cysticidal activity against Taenia crassiceps cysts after 11 days by trypan blue exclusion method
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Taenia crassiceps
Confidence 1 — Organism
Curated By Autocuration

Target

Taenia crassiceps (CHEMBL612894)
Type ORGANISM
Organism Taenia crassiceps

Publication

Medicinal plants used as anthelmintics: Ethnomedical, pharmacological, and phytochemical studies.
Romero-Benavides JC, Ruano AL, Silva-Rivas R, Castillo-Veintimilla P, Vivanco-Jaramillo S, Bailon-Moscoso N.
Eur J Med Chem (2017) 129 : 209 -217
PubMed 28231520 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 3 5.27 6.00

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4080319 1 6.00
CHEMBL399910 PINOCEMBRIN 2.0 1 5.70
CHEMBL117 CHRYSIN 1 4.10

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4080319 IC50 = 1000.0 nM 6.00
CHEMBL399910 PINOCEMBRIN IC50 = 2000.0 nM 5.70
CHEMBL117 CHRYSIN IC50 = 80000.0 nM 4.10