Assay Detail
Functional
CHEMBL4006933
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Nematocidal activity against Caenorhabditis elegans
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Caenorhabditis elegans |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Medicinal plants used as anthelmintics: Ethnomedical, pharmacological, and phytochemical studies.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 8 | 4.59 | 5.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL289191 | LUPEOL | — | 1 | 5.30 |
| CHEMBL4059696 | — | — | 1 | 4.52 |
| CHEMBL169 | URSOLIC ACID | 2.0 | 1 | 4.30 |
| CHEMBL4104618 | — | — | 1 | 4.22 |
| CHEMBL269277 | BETULINIC ACID | 1.0 | 1 | - |
| CHEMBL42710 | EUGENOL | 0.5 | 1 | - |
| CHEMBL164660 | PSORALEN | 1.0 | 1 | - |
| CHEMBL4061332 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL289191 | LUPEOL | IC50 | = | 5000.0 | nM | 5.30 |
| CHEMBL4059696 | — | IC50 | = | 30000.0 | nM | 4.52 |
| CHEMBL169 | URSOLIC ACID | IC50 | = | 50000.0 | nM | 4.30 |
| CHEMBL4104618 | — | IC50 | = | 60000.0 | nM | 4.22 |
| CHEMBL269277 | BETULINIC ACID | IC50 | = | 150000.0 | nM | - |
| CHEMBL42710 | EUGENOL | IC50 | = | 370000.0 | nM | - |
| CHEMBL164660 | PSORALEN | IC50 | = | 641370000.0 | nM | - |
| CHEMBL4061332 | — | IC50 | = | 140000.0 | nM | - |