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Assay Detail

CHEMBL4006936

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Nematocidal activity against Nippostrongylus brasiliensis L4 larval stage
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Nippostrongylus brasiliensis
Confidence 1 — Organism
Curated By Autocuration

Target

Nippostrongylus brasiliensis (CHEMBL613822)
Type ORGANISM
Organism Nippostrongylus brasiliensis

Publication

Medicinal plants used as anthelmintics: Ethnomedical, pharmacological, and phytochemical studies.
Romero-Benavides JC, Ruano AL, Silva-Rivas R, Castillo-Veintimilla P, Vivanco-Jaramillo S, Bailon-Moscoso N.
Eur J Med Chem (2017) 129 : 209 -217
PubMed 28231520 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 7 4.53 4.66

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4097168 1 4.66
CHEMBL4104192 1 4.55
CHEMBL4096461 1 4.47
CHEMBL4069217 1 4.43
CHEMBL4066509 1 -
CHEMBL4079952 1 -
CHEMBL4069967 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4097168 IC50 = 22000.0 nM 4.66
CHEMBL4104192 IC50 = 28000.0 nM 4.55
CHEMBL4096461 IC50 = 34000.0 nM 4.47
CHEMBL4069217 IC50 = 37000.0 nM 4.43
CHEMBL4066509 IC50 = 106000.0 nM -
CHEMBL4079952 IC50 = 121000.0 nM -
CHEMBL4069967 IC50 = 118000.0 nM -