Assay Detail
Functional
CHEMBL4007984
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Antibiofilm activity against Candida albicans CAF2-1 after 48 hrs by Alamar blue assay
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Candida albicans |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Tackling Fungal Resistance by Biofilm Inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 5.65 | 6.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1454910 | NITROXOLINE | 4.0 | 1 | 6.00 |
| CHEMBL1200596 | CHLOROXINE | 4.0 | 1 | 5.92 |
| CHEMBL1484167 | — | — | 1 | 5.77 |
| CHEMBL1382917 | — | — | 1 | 5.55 |
| CHEMBL1450615 | — | — | 1 | 5.01 |
| CHEMBL1404493 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1454910 | NITROXOLINE | IC50 | = | 1000.0 | nM | 6.00 |
| CHEMBL1200596 | CHLOROXINE | IC50 | = | 1200.0 | nM | 5.92 |
| CHEMBL1484167 | — | IC50 | = | 1700.0 | nM | 5.77 |
| CHEMBL1382917 | — | IC50 | = | 2800.0 | nM | 5.55 |
| CHEMBL1450615 | — | IC50 | = | 9800.0 | nM | 5.01 |
| CHEMBL1404493 | — | IC50 | = | 230900.0 | nM | - |