Assay Detail
Binding
CHEMBL4008026
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Binding affinity to MR (unknown origin)
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Modulating Mineralocorticoid Receptor with Non-steroidal Antagonists. New Opportunities for the Development of Potent and Selective Ligands without Off-Target Side Effects.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 3 | 9.30 | 9.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL110739 | CORTICOSTERONE | 3.0 | 1 | 9.30 |
| CHEMBL389621 | HYDROCORTISONE | 4.0 | 1 | 9.30 |
| CHEMBL273453 | ALDOSTERONE | 2.0 | 1 | 9.30 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL110739 | CORTICOSTERONE | Kd | = | 0.5 | nM | 9.30 |
| CHEMBL389621 | HYDROCORTISONE | Kd | = | 0.5 | nM | 9.30 |
| CHEMBL273453 | ALDOSTERONE | Kd | = | 0.5 | nM | 9.30 |