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Assay Detail

CHEMBL4008229

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Binding
Inhibition of influenza A virus PA endonuclease
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Influenza A virus
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Inhibitors of Influenza Virus Polymerase Acidic (PA) Endonuclease: Contemporary Developments and Perspectives.
Ju H, Zhang J, Huang B, Kang D, Huang B, Liu X, Zhan P.
J Med Chem (2017) 60 : 3533 -3551
PubMed 28118010 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 2 5.02 5.30

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL2040563 1 5.30
CHEMBL2040562 1 4.73

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL2040563 Ki = 5010.0 nM 5.30
CHEMBL2040562 Ki = 18700.0 nM 4.73