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Assay Detail

CHEMBL4008235

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiviral activity against influenza A virus H5N1 infected in MDCK cells assessed as reduction of virus-induced cytopathic effect after 48 hrs by CellTiter-Glo luminescent assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism H5N1 subtype
Confidence 1 — Organism
Curated By Autocuration

Target

H5N1 subtype (CHEMBL613845)
Type ORGANISM
Organism H5N1 subtype

Publication

Inhibitors of Influenza Virus Polymerase Acidic (PA) Endonuclease: Contemporary Developments and Perspectives.
Ju H, Zhang J, Huang B, Kang D, Huang B, Liu X, Zhan P.
J Med Chem (2017) 60 : 3533 -3551
PubMed 28118010 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 7.86 7.86

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4103104 1 7.86

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4103104 EC50 = 13.9 nM 7.86