Assay Detail
Binding
CHEMBL4008885
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of hyaluronidase (unknown origin) using hyaluronic acid as substrate preincubated for 20 mins followed by CaCl2 activation for 20 mins and subsequent substrate addition measured after 10 mins by colorimetric method
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Discovery of hyaluronidase inhibitors from natural products and their mechanistic characterization under DMSO-perturbed assay conditions.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 4.52 | 4.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1773982 | — | — | 1 | 4.52 |
| CHEMBL583912 | (-)-EPICATECHIN | 2.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1773982 | — | IC50 | = | 30000.0 | nM | 4.52 |
| CHEMBL583912 | (-)-EPICATECHIN | IC50 | = | 685000.0 | nM | - |