Assay Detail
Binding
CHEMBL4009979
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Displacement of [3H]DTG from sigma receptor (unknown origin)
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
The 2014 Philip S. Portoghese Medicinal Chemistry Lectureship: The "Phenylalkylaminome" with a Focus on Selected Drugs of Abuse.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 6 | 6.82 | 8.20 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL268969 | — | — | 1 | 8.20 |
| CHEMBL4088752 | — | — | 1 | 7.66 |
| CHEMBL4089319 | — | — | 1 | 7.55 |
| CHEMBL74019 | — | — | 1 | 6.82 |
| CHEMBL274099 | — | — | 1 | 6.37 |
| CHEMBL612 | DEXTROAMPHETAMINE | 4.0 | 1 | 4.34 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL268969 | — | Ki | = | 6.3 | nM | 8.20 |
| CHEMBL4088752 | — | Ki | = | 22.0 | nM | 7.66 |
| CHEMBL4089319 | — | Ki | = | 28.0 | nM | 7.55 |
| CHEMBL74019 | — | Ki | = | 150.0 | nM | 6.82 |
| CHEMBL274099 | — | Ki | = | 430.0 | nM | 6.37 |
| CHEMBL612 | DEXTROAMPHETAMINE | Ki | = | 46000.0 | nM | 4.34 |