Assay Detail
Binding
CHEMBL4010765
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to HCV IRES 5'Alexa488-GCCGAGGAGUGUUGGGUCGCGCAAGGC-3' RNA at 20 degC after overnight incubation by fluorescence assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Hepacivirus hominis |
| Confidence | 3 — Cell-line / Tissue |
| Curated By | Autocuration |
Target
Internal ribosome entry site (IRES) (CHEMBL612412) ↗| Type | NUCLEIC-ACID |
| Organism | Hepacivirus hominis |
Publication
Assessment of new triplet forming artificial nucleobases as RNA ligands directed towards HCV IRES IIId loop.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 3 | 4.38 | 4.38 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4096823 | — | — | 1 | 4.38 |
| CHEMBL4104947 | — | — | 1 | - |
| CHEMBL4097244 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4096823 | — | Kd | = | 41400.0 | nM | 4.38 |
| CHEMBL4104947 | — | Kd | - | — | - | |
| CHEMBL4097244 | — | Kd | = | 554400.0 | nM | - |