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Assay Detail

CHEMBL4012485

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of monkey CYP11B2
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Macaca mulatta
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

4-Anilino-pyrimidine, novel aldosterone synthase (CYP11B2) inhibitors bearing pyrimidine structures.
Meguro M, Miyauchi S, Kanao Y, Naito S, Suzuki K, Inoue S, Yamada K, Homma T, Chiba K, Nara F, Furuzono S.
Bioorg Med Chem Lett (2017) 27 : 1902 -1906
PubMed 28359792 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 8.57 8.57

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4099824 1 8.57

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4099824 IC50 = 2.7 nM 8.57