Assay Detail
Functional
CHEMBL4012805
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Antiviral activity against Human rhinovirus A16 infected in human H1HeLa cells assessed as protection against virus induced cytopathic effect after 3 days by MTT assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | rhinovirus A16 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
A Novel Series of Highly Potent Small Molecule Inhibitors of Rhinovirus Replication.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 3 | 6.87 | 7.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL20210 | RUPINTRIVIR | 2.0 | 1 | 7.52 |
| CHEMBL4086772 | — | — | 1 | 6.64 |
| CHEMBL29609 | PLECONARIL | 2.0 | 1 | 6.46 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL20210 | RUPINTRIVIR | EC50 | = | 30.0 | nM | 7.52 |
| CHEMBL4086772 | — | EC50 | = | 230.0 | nM | 6.64 |
| CHEMBL29609 | PLECONARIL | EC50 | = | 350.0 | nM | 6.46 |