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Assay Detail

CHEMBL4013244

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antioxidant activity assessed as DPPH free radical scavenging after 40 mins incubation in dark
2
Total Activities
2
Compounds Tested
2
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Publication

Donepezil-Based Central Acetylcholinesterase Inhibitors by Means of a "Bio-Oxidizable" Prodrug Strategy: Design, Synthesis, and in Vitro Biological Evaluation.
Peauger L, Azzouz R, Gembus V, Ţînţaş ML, Sopková-de Oliveira Santos J, Bohn P, Papamicaël C, Levacher V.
J Med Chem (2017) 60 : 5909 -5926
PubMed 28613859 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Activity 1 - -
EC50 1 4.05 4.05

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4101303 1 4.05
CHEMBL502 DONEPEZIL 4.0 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4101303 EC50 = 90000.0 nM 4.05
CHEMBL502 DONEPEZIL Activity - -