Assay Detail
Functional
CHEMBL4016844
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of U46619-induced contractions in porcine coronary artery rings
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Sus scrofa |
| Tissue | Artery |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Discovery of the Soluble Guanylate Cyclase Stimulator Vericiguat (BAY 1021189) for the Treatment of Chronic Heart Failure.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 6.02 | 6.02 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4066936 | VERICIGUAT | 4.0 | 1 | 6.02 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4066936 | VERICIGUAT | IC50 | = | 956.0 | nM | 6.02 |