Assay Detail
Binding
CHEMBL4017034
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human ERG
5
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Voltage-gated inwardly rectifying potassium channel KCNH2 (CHEMBL240) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Design, Multicomponent Synthesis, and Anticancer Activity of a Focused Histone Deacetylase (HDAC) Inhibitor Library with Peptoid-Based Cap Groups.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 4.72 | 5.65 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL391514 | — | — | 1 | 5.65 |
| CHEMBL4063658 | — | — | 2 | 4.67 |
| CHEMBL4069631 | — | — | 2 | 4.29 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL391514 | — | IC50 | = | 2228.44 | nM | 5.65 |
| CHEMBL4063658 | — | IC50 | = | 21527.82 | nM | 4.67 |
| CHEMBL4069631 | — | IC50 | = | 50815.94 | nM | 4.29 |
| CHEMBL4063658 | — | IC50 | = | 52119.47 | nM | 4.28 |
| CHEMBL4069631 | — | IC50 | = | 279898.13 | nM | - |