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Assay Detail

CHEMBL4017952

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiplasmodial activity against chloroquine-sensitive Plasmodium falciparum 3D7
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Plasmodium falciparum
Confidence 1 — Organism
Curated By Autocuration

Target

Plasmodium falciparum (CHEMBL364)
Type ORGANISM
Organism Plasmodium falciparum

Publication

Antiplasmodial β-triketones from the flowers of the Australian tree Angophora woodsiana.
Senadeera SPD, Duffy S, Avery VM, Carroll AR.
Bioorg Med Chem Lett (2017) 27 : 2602 -2607
PubMed 28400231 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 3 5.94 6.54

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4078793 1 6.54
CHEMBL4071359 1 6.00
CHEMBL4098940 1 5.28

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4078793 IC50 = 290.0 nM 6.54
CHEMBL4071359 IC50 = 1000.0 nM 6.00
CHEMBL4098940 IC50 = 5300.0 nM 5.28