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Assay Detail

CHEMBL4019778

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Binding
Binding affinity to human TRPV1 expressed in CHO cells after 45 mins by scintillation counting method
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Publication

Novel Radiolabeled Vanilloid with Enhanced Specificity for Human Transient Receptor Potential Vanilloid 1 (TRPV1).
Pearce LV, Ann J, Jung A, Thorat SA, Herold BKA, Habtemichael AD, Blumberg PM, Lee J.
J Med Chem (2017) 60 : 8246 -8252
PubMed 28892388 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Kd 3 9.12 9.23

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4095861 1 9.23
CHEMBL4077829 1 9.23
CHEMBL4060041 1 8.91

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4095861 Kd = 0.589 nM 9.23
CHEMBL4077829 Kd = 0.59 nM 9.23
CHEMBL4060041 Kd = 1.23 nM 8.91