Assay Detail
Binding
CHEMBL4021116
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to Electric eel AChE
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Electrophorus electricus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Stereospecific cholinesterase inhibition by O,S-diethylphenylphosphonothioate.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 3 | 5.92 | 6.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL15910 | SOMAN | — | 1 | 6.40 |
| CHEMBL4085438 | — | — | 1 | 5.70 |
| CHEMBL509554 | ISOPROPYL METHYLPHOSPHONOFLUORIDATE | — | 1 | 5.66 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL15910 | SOMAN | Kd | = | 400.0 | nM | 6.40 |
| CHEMBL4085438 | — | Kd | = | 2000.0 | nM | 5.70 |
| CHEMBL509554 | ISOPROPYL METHYLPHOSPHONOFLUORIDATE | Kd | = | 2200.0 | nM | 5.66 |