Assay Detail
Binding
CHEMBL4022156
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of HCV NS3/4A protease using AcDTEDVVP(Nva)-O-PAP as substrate pretreated with substrate for 3 mins followed by enzyme addition measured after 60 mins by spectrophotometric method
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Hepatitis C virus |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
QSAR studies of the bioactivity of hepatitis C virus (HCV) NS3/4A protease inhibitors by multiple linear regression (MLR) and support vector machine (SVM).
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 1 | 7.85 | 7.85 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL218394 | BOCEPREVIR | 4.0 | 1 | 7.85 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL218394 | BOCEPREVIR | Ki | = | 14.0 | nM | 7.85 |