Assay Detail
Functional
CHEMBL4022433
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Cytotoxicity against human Hs578T cells assessed as decrease in cell viability after 120 hrs by MTS assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | Hs-578T |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Quinazolinone derivatives as inhibitors of homologous recombinase RAD51.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.20 | 5.38 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1887735 | — | — | 1 | 5.38 |
| CHEMBL1567670 | — | — | 1 | 5.02 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1887735 | — | IC50 | = | 4200.0 | nM | 5.38 |
| CHEMBL1567670 | — | IC50 | = | 9600.0 | nM | 5.02 |