Assay Detail
Binding
CHEMBL4023929
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to human N-terminal full length His-tagged CA13 (1 to 262 residues) expressed in Escherichia coli BL21(DE3) assessed as thermodynamic equilibrium constant at pH 7 by SPR assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Introduction of Intrinsic Kinetics of Protein-Ligand Interactions and Their Implications for Drug Design.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 3 | 7.09 | 7.92 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4085190 | — | — | 1 | 7.92 |
| CHEMBL20 | ACETAZOLAMIDE | 4.0 | 1 | 7.44 |
| CHEMBL3799296 | — | — | 1 | 5.92 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4085190 | — | Kd | = | 12.0 | nM | 7.92 |
| CHEMBL20 | ACETAZOLAMIDE | Kd | = | 36.5 | nM | 7.44 |
| CHEMBL3799296 | — | Kd | = | 1200.0 | nM | 5.92 |