Assay Detail
Binding
CHEMBL4024869
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Inhibition of PI3K (unknown origin)
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Covalent Modifiers: A Chemical Perspective on the Reactivity of α,β-Unsaturated Carbonyls with Thiols via Hetero-Michael Addition Reactions.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 9.48 | 10.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4059992 | — | — | 1 | 10.00 |
| CHEMBL4082872 | — | — | 1 | 9.52 |
| CHEMBL4088236 | — | — | 1 | 9.30 |
| CHEMBL428496 | WORTMANNIN | — | 1 | 9.10 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4059992 | — | IC50 | = | 0.1 | nM | 10.00 |
| CHEMBL4082872 | — | IC50 | = | 0.3 | nM | 9.52 |
| CHEMBL4088236 | — | IC50 | = | 0.5 | nM | 9.30 |
| CHEMBL428496 | WORTMANNIN | IC50 | = | 0.8 | nM | 9.10 |