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Assay Detail

CHEMBL4025855

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Cytotoxicity against human K562 cells after 24 hrs by MTT assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type K562
Confidence 1 — Organism
Curated By Autocuration

Target

K562 (CHEMBL385)
Type CELL-LINE
Organism Homo sapiens

Publication

Anthranilamide-based 2-phenylcyclopropane-1-carboxamides, 1,1'-biphenyl-4-carboxamides and 1,1'-biphenyl-2-carboxamides: Synthesis biological evaluation and mechanism of action.
Raffa D, Plescia F, Maggio B, Raimondi MV, D'Anneo A, Lauricella M, Daidone G.
Eur J Med Chem (2017) 132 : 262 -273
PubMed 28365319 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.30 6.30

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4086160 1 6.30

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4086160 IC50 = 500.0 nM 6.30