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Assay Detail

CHEMBL4025858

Review assay metadata, readout intent, target linkage, and publication context from the same page.

ADMET
Cytotoxicity against human 16HBE cells after 24 hrs by MTT assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type ADMET
Organism Homo sapiens
Cell Type 16HBE14o-
Confidence 1 — Organism
Curated By Autocuration

Target

16HBE14o- (CHEMBL4296395)
Type CELL-LINE
Organism Homo sapiens

Publication

Anthranilamide-based 2-phenylcyclopropane-1-carboxamides, 1,1'-biphenyl-4-carboxamides and 1,1'-biphenyl-2-carboxamides: Synthesis biological evaluation and mechanism of action.
Raffa D, Plescia F, Maggio B, Raimondi MV, D'Anneo A, Lauricella M, Daidone G.
Eur J Med Chem (2017) 132 : 262 -273
PubMed 28365319 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 4.52 4.52

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4086160 1 4.52

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4086160 IC50 = 30000.0 nM 4.52