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Assay Detail

CHEMBL4026320

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of bacterial AmpC
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Bacteria
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Pharmaceutical Approaches to Target Antibiotic Resistance Mechanisms.
Schillaci D, Spanò V, Parrino B, Carbone A, Montalbano A, Barraja P, Diana P, Cirrincione G, Cascioferro S.
J Med Chem (2017) 60 : 8268 -8297
PubMed 28594170 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 2 9.70 10.30

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3613796 1 10.30
CHEMBL4094945 1 9.10

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3613796 Ki = 0.05 nM 10.30
CHEMBL4094945 Ki = 0.8 nM 9.10