Assay Detail
Binding
CHEMBL4026324
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Inhibition of Escherichia coli PBP2
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Escherichia coli |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Pharmaceutical Approaches to Target Antibiotic Resistance Mechanisms.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 4.99 | 5.50 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4088713 | — | — | 1 | 5.50 |
| CHEMBL4075020 | — | — | 1 | 5.44 |
| CHEMBL4067473 | — | — | 1 | 4.80 |
| CHEMBL2107817 | AVIBACTAM SODIUM | 4.0 | 1 | 4.20 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4088713 | — | IC50 | = | 3200.0 | nM | 5.50 |
| CHEMBL4075020 | — | IC50 | = | 3600.0 | nM | 5.44 |
| CHEMBL4067473 | — | IC50 | = | 16000.0 | nM | 4.80 |
| CHEMBL2107817 | AVIBACTAM SODIUM | IC50 | = | 63000.0 | nM | 4.20 |