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Assay Detail

CHEMBL4026336

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of Escherichia coli DH5alpha TEM-1 using nitrocefin as substrate preincubated for 5 mins followed by substrate addition
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Escherichia coli DH5[alpha]
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Pharmaceutical Approaches to Target Antibiotic Resistance Mechanisms.
Schillaci D, Spanò V, Parrino B, Carbone A, Montalbano A, Barraja P, Diana P, Cirrincione G, Cascioferro S.
J Med Chem (2017) 60 : 8268 -8297
PubMed 28594170 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 7.92 7.92

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1645238 1 7.92

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1645238 IC50 = 12.0 nM 7.92