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Assay Detail

CHEMBL4026538

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Functional
Antiproliferative activity against human MV4-11 cells assessed as decrease in cell viability measured at day 4 by Cell-Titer Glo assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type MV4-11
Confidence 1 — Organism
Curated By Autocuration

Target

MV4-11 (CHEMBL613835)
Type CELL-LINE
Organism Homo sapiens

Publication

Development of Potent Type I Protein Arginine Methyltransferase (PRMT) Inhibitors of Leukemia Cell Proliferation.
Wang C, Jiang H, Jin J, Xie Y, Chen Z, Zhang H, Lian F, Liu YC, Zhang C, Ding H, Chen S, Zhang N, Zhang Y, Jiang H, Chen K, Ye F, Yao Z, Luo C.
J Med Chem (2017) 60 : 8888 -8905
PubMed 29019697 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.34 5.34

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4094513 1 5.34

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4094513 IC50 = 4550.0 nM 5.34