Assay Detail
Binding
CHEMBL4027952
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Inhibition of human DCLRE1B
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
In Silico Fragment-Based Design Identifies Subfamily B1 Metallo-β-lactamase Inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 3.71 | 3.83 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4076158 | — | — | 1 | 3.83 |
| CHEMBL4088063 | — | — | 1 | 3.73 |
| CHEMBL4092378 | — | — | 1 | 3.57 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4076158 | — | IC50 | = | 149000.0 | nM | 3.83 |
| CHEMBL4088063 | — | IC50 | = | 185000.0 | nM | 3.73 |
| CHEMBL4092378 | — | IC50 | = | 268000.0 | nM | 3.57 |