Assay Detail
Functional
CHEMBL4029426
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Induction of proton motive force collapse in Escherichia coli inverted membrane vesicle in presence of ATP-driven PMF generation system by ACMA-based fluorescence assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Escherichia coli |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Phenylthiazole Antibacterial Agents Targeting Cell Wall Synthesis Exhibit Potent Activity in Vitro and in Vivo against Vancomycin-Resistant Enterococci.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 5.66 | 6.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL224214 | CARBONYL CYANIDE M-CHLOROPHENYLHYDRAZONE | — | 1 | 6.40 |
| CHEMBL1798027 | — | — | 1 | 4.92 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL224214 | CARBONYL CYANIDE M-CHLOROPHENYLHYDRAZONE | EC50 | = | 400.0 | nM | 6.40 |
| CHEMBL1798027 | — | EC50 | = | 12000.0 | nM | 4.92 |