Assay Detail
Binding
CHEMBL4030325
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of amyloid beta binding to biotin-labeled human RAGE domain V after 60 mins by ELISA
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Advanced glycosylation end product-specific receptor (CHEMBL2176846) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Targeting the Receptor for Advanced Glycation Endproducts (RAGE): A Medicinal Chemistry Perspective.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.25 | 5.72 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3235375 | — | — | 1 | 5.72 |
| CHEMBL2179073 | — | — | 1 | 4.78 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3235375 | — | IC50 | = | 1900.0 | nM | 5.72 |
| CHEMBL2179073 | — | IC50 | = | 16500.0 | nM | 4.78 |