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Assay Detail

CHEMBL4031914

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Displacement of [Tyrosyl-2,6-3H]Oxytocin from recombinant mouse OTR expressed in CHO-K1 cells after 180 mins by liquid scintillation counting method
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Mus musculus
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Oxytocin receptor (CHEMBL3243907)
Type SINGLE PROTEIN
Organism Mus musculus

Publication

Targets for Drug Therapy for Autism Spectrum Disorder: Challenges and Future Directions.
Lacivita E, Perrone R, Margari L, Leopoldo M.
J Med Chem (2017) 60 : 9114 -9141
PubMed 29039668 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 7.29 7.29

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3763342 1 7.29

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3763342 Ki = 51.6 nM 7.29