Assay Detail
Functional
CHEMBL4032014
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antimicrobial activity against Chlamydia trachomatis serovar D UW-3 infected in human HeLa229 cells assessed as reduction in reinfection levels measured 44 to 48 hrs post infection by DAPI staining-based assay
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Chlamydia trachomatis |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Thiazolino 2-Pyridone Amide Isosteres As Inhibitors of Chlamydia trachomatis Infectivity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 5 | 7.45 | 7.46 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4087188 | — | — | 1 | 7.46 |
| CHEMBL4074384 | — | — | 1 | 7.43 |
| CHEMBL4094870 | — | — | 1 | - |
| CHEMBL4075283 | — | — | 1 | - |
| CHEMBL4102617 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4087188 | — | EC50 | = | 35.0 | nM | 7.46 |
| CHEMBL4074384 | — | EC50 | = | 37.0 | nM | 7.43 |
| CHEMBL4094870 | — | EC50 | - | — | - | |
| CHEMBL4075283 | — | EC50 | - | — | - | |
| CHEMBL4102617 | — | EC50 | - | — | - |