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Assay Detail

CHEMBL4032879

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity to human BRD9 (R130 to V259) expressed in bacterial cells by BromoScan assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Bromodomain-containing protein 9 (CHEMBL3108640)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

A Unique Approach to Design Potent and Selective Cyclic Adenosine Monophosphate Response Element Binding Protein, Binding Protein (CBP) Inhibitors.
Bronner SM, Murray J, Romero FA, Lai KW, Tsui V, Cyr P, Beresini MH, de Leon Boenig G, Chen Z, Choo EF, Clark KR, Crawford TD, Jayaram H, Kaufman S, Li R, Li Y, Liao J, Liang X, Liu W, Ly J, Maher J, Wai J, Wang F, Zheng A, Zhu X, Magnuson S.
J Med Chem (2017) 60 : 10151 -10171
PubMed 29155580 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Kd 1 5.44 5.44

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4061254 1 5.44

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4061254 Kd = 3600.0 nM 5.44