Assay Detail
Functional
CHEMBL4033810
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Cytotoxicity against human MDA-MB-435 cells incubated for 72 hrs by CellTiter 96 aqueous one solution cell proliferation assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | MDA-MB-435 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Cardiac Glycoside Constituents of Streblus asper with Potential Antineoplastic Activity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 8.38 | 9.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL428647 | PACLITAXEL | 4.0 | 1 | 9.70 |
| CHEMBL449686 | STREBLOSIDE | — | 1 | 7.05 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL428647 | PACLITAXEL | IC50 | = | 0.2 | nM | 9.70 |
| CHEMBL449686 | STREBLOSIDE | IC50 | = | 90.0 | nM | 7.05 |